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As tTG2 is vital to the development of celiac disease, selective inhibition of tTG2 could be another potential therapeutic approach for celiac disease (Kupfer 2012

Fish Shellfish Immunol 44:195202

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The MINE score could also be useful in identifying asymptomatic dogs with higher risk of cardiac death." In an August 2025 article, the same team of Italian veterinary cardiology researchers have re-examined their MINE formulation using 749 dogs, including 129 (17.2%) cavalier King Charles spaniels